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Conditional Hypoxia Inducible Factor-1α Induction in Embryonic Pulmonary Epithelium Impairs Maturation and Augments Lymphangiogenesis

Hypoxia inducible factor (HIF) 1a, EPAS1 and NEPAS are expressed in the embryonic mouse lung and each isoform exhibits distinct spatiotemporal expression patterns throughout morphogenesis. To further assess the role of the HIF1a isoform in lung epithelial cell differentiation and homeostasis, we cre...

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Detalhes bibliográficos
Main Authors: Bridges, James P., Lin, Sui, Ikegami, Machiko, Shannon, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262673/
https://ncbi.nlm.nih.gov/pubmed/22094019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.10.033
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