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Therapeutic Value of Small Molecule Inhibitor to Plasminogen Activator Inhibitor–1 for Lung Fibrosis

Fibrosis is a final stage of many lung diseases, with no effective treatment. Plasminogen activator inhibitor–1 (PAI-1), a primary inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA, respectively), plays a critical role in the development of fibrosis. In this study, we e...

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Detalhes bibliográficos
Main Authors: Huang, Wen-Tan, Vayalil, Praveen K., Miyata, Toshio, Hagood, James, Liu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262658/
https://ncbi.nlm.nih.gov/pubmed/21852684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0139OC
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