Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disorder with unknown cause and no effective treatment. The incidence of and mortality from IPF increase with age, suggesting that advanced age is a major risk factor for IPF. The mechanism underlying the increased susceptibility of the elderly to...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Huang, Wen-Tan, Akhter, Hasina, Jiang, Chunsun, MacEwen, Mark, Ding, Qiang, Antony, Veena, Thannickal, Victor John, Liu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384687/
https://ncbi.nlm.nih.gov/pubmed/25451236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.11.018
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