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A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen

About two thirds of all human breast cancer cases are estrogen receptor positive. The drug of first choice for these patients is tamoxifen. However, about half of the recurrences after removal of the primary tumor are or become resistant to this drug. While many mechanisms have been identified for t...

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Detalhes bibliográficos
Main Authors: de Leeuw, Renée, Neefjes, Jacques, Michalides, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262574/
https://ncbi.nlm.nih.gov/pubmed/22295213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/232435
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