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A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen

About two thirds of all human breast cancer cases are estrogen receptor positive. The drug of first choice for these patients is tamoxifen. However, about half of the recurrences after removal of the primary tumor are or become resistant to this drug. While many mechanisms have been identified for t...

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Bibliografiske detaljer
Main Authors: de Leeuw, Renée, Neefjes, Jacques, Michalides, Rob
Format: Artigo
Sprog:Inglês
Udgivet: SAGE-Hindawi Access to Research 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262574/
https://ncbi.nlm.nih.gov/pubmed/22295213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/232435
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