Use of methylphosphonic dichloride for the synthesis of oligonucleoside methylphosphonates.

Methylphosphonic dichloride was used to prepare protected deoxyribonucleoside 3'-methylphosphonate beta-cyanoethyl esters, d-[(MeO)2Tr]NpCNEt, and protected oligonucleoside methylphosphonates in solution. Reaction of d-[(MeO)2Tr]N with methylphosphonic dichloride gives d-[(MeO)2Tr]NpCl. The pho...

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Publicado en:Nucleic Acids Res
Main Authors: Miller, P S, Agris, C H, Blandin, M, Murakami, A, Reddy, P M, Spitz, S A, Ts'o, P O
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1983
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326248/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6878043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.15.5189
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