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Hedgehog Signaling Regulates Nociceptive Sensitization

BACKGROUND: Nociceptive sensitization is a tissue damage response whereby sensory neurons near damaged tissue enhance their responsiveness to external stimuli. This sensitization manifests as allodynia (aversive withdrawal to previously nonnoxious stimuli) and/or hyperalgesia (exaggerated responsive...

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Bibliographic Details
Main Authors: Babcock, Daniel T., Shi, Shanping, Jo, Juyeon, Shaw, Michael, Gutstein, Howard B., Galko, Michael J.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262399/
https://ncbi.nlm.nih.gov/pubmed/21906949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.08.020
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