Drosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization

Tumor necrosis factor (TNF) signaling is required for inflammatory nociceptive (pain) sensitization in Drosophila and vertebrates. Nociceptive sensitization in Drosophila larvae following UV-induced tissue damage is accompanied by epidermal apoptosis and requires epidermal-derived TNF/Eiger and the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jo, Juyeon, Im, Seol Hee, Babcock, Daniel T, Iyer, Srividya C, Gunawan, Felona, Cox, Daniel N, Galko, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520682/
https://ncbi.nlm.nih.gov/pubmed/28492538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.474
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