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Genetic and proteomic approaches to identify cancer drug targets

While target-based small-molecule discovery has taken centre-stage in the pharmaceutical industry, there are many cancer-promoting proteins not easily addressed with a traditional target-based screening approach. In order to address this problem, as well as to identify modulators of biological state...

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Detalhes bibliográficos
Main Authors: Roti, G, Stegmaier, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262130/
https://ncbi.nlm.nih.gov/pubmed/22166799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.543
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