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Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes

The carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II) comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Reversible phosphorylation of Ser2, Ser5, and Ser7 during the transcription cycle mediates the sequential recruitment of t...

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Autori principali: Egloff, Sylvain, Zaborowska, Justyna, Laitem, Clélia, Kiss, Tamás, Murphy, Shona
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262128/
https://ncbi.nlm.nih.gov/pubmed/22137580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.006
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