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Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis

Extracellular superoxide dismutase (EcSOD) is an important superoxide scavenger in the lung where its loss, sequence variation, or abnormal expression contributes to lung diseases; however, the role of EcSOD in lung cancer has yet to be studied. We hypothesized that EcSOD loss could affect malignant...

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Detalles Bibliográficos
Main Authors: Teoh, Melissa L.T., Fitzgerald, Matthew P., Jensen, Taylor J., Futscher, Bernard W., Domann, Frederick E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262094/
https://ncbi.nlm.nih.gov/pubmed/22064654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0501
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