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Effects of pH on proteins: Predictions for ensemble and single molecule pulling experiments

Protein conformations change among distinct thermodynamic states as solution conditions (temperature, denaturants, pH) are altered or when they are subject to mechanical forces. A quantitative description of the changes in the relative stabilities of the various thermodynamic states is needed to int...

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Detalhes bibliográficos
Main Authors: O’Brien, Edward P., Brooks, Bernard R., Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262061/
https://ncbi.nlm.nih.gov/pubmed/22148729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja206557y
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