Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias

BACKGROUND: Skin stem cells contribute to all three major lineages of epidermal appendages, i.e., the epidermis, the hair follicle, and the sebaceous gland. In hair follicles, highly proliferative committed progenitor cells, called matrix cells, are located at the base of the follicle in the hair bu...

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Autori principali: Kan, Lixin, Liu, Yijie, McGuire, Tammy L, Bonaguidi, Michael A, Kessler, John A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262035/
https://ncbi.nlm.nih.gov/pubmed/22168923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-92
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