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Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
Using conditional gene targeting in mice, we show that BMP receptor IA is essential for the differentiation of progenitor cells of the inner root sheath and hair shaft. Without BMPRIA activation, GATA-3 is down-regulated and its regulated control of IRS differentiation is compromised. In contrast, L...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173651/ https://ncbi.nlm.nih.gov/pubmed/14610062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309042 |
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