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Dynamics of HBV cccDNA expression and transcription in different cell growth phase

BACKGROUND: The covalently closed-circular DNA (cccDNA) of hepatitis B virus (HBV) is associated with viral persistence in HBV-infected hepatocytes. However, the regulation of cccDNA and its transcription in the host cells at different growth stages is not well understood. METHODS: We took advantage...

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Bibliografiske detaljer
Main Authors: Chong, Chin-Liew, Chen, Mong-Liang, Wu, Yi-Chieh, Tsai, Kuen-Nan, Huang, Chien-Chiao, Hu, Cheng-po, Jeng, King-Song, Chou, Yu-Chi, Chang, Chungming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262020/
https://ncbi.nlm.nih.gov/pubmed/22208719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-96
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