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Estrogen Receptor-Alpha 36 Mediates Mitogenic Antiestrogen Signaling in ER-Negative Breast Cancer Cells

It is prevailingly thought that the antiestrogens tamoxifen and ICI 182, 780 are competitive antagonists of the estrogen-binding site of the estrogen receptor-alpha (ER-α). However, a plethora of evidence demonstrated both antiestrogens exhibit agonist activities in different systems such as activat...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, XinTian, Ding, Ling, Kang, LianGuo, Wang, Zhao-Yi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261853/
https://ncbi.nlm.nih.gov/pubmed/22276155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030174
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