Functional impairment of Tax-specific but not cytomegalovirus-specific CD8(+ )T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a small percentage of infected individuals. ATL is often associated with general immune suppression and an impaired HTLV-1-specific T-...

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Bibliografiska uppgifter
Huvudupphovsmän: Takamori, Ayako, Hasegawa, Atsuhiko, Utsunomiya, Atae, Maeda, Yasuhiro, Yamano, Yoshihisa, Masuda, Masato, Shimizu, Yukiko, Tamai, Yotaro, Sasada, Amane, Zeng, Na, Choi, Ilseung, Uike, Naokuni, Okamura, Jun, Watanabe, Toshiki, Masuda, Takao, Kannagi, Mari
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261825/
https://ncbi.nlm.nih.gov/pubmed/22151736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-100
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