VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR)-2 and VEGFR-3 have been implicated in angiogenic sprouting. Surprisingly, we f...

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Auteurs principaux: Tammela, Tuomas, Zarkada, Georgia, Nurmi, Harri, Jakobsson, Lars, Heinolainen, Krista, Tvorogov, Denis, Zheng, Wei, Franco, Claudio A., Murtomäki, Aino, Aranda, Evelyn, Miura, Naoyuki, Ylä-Herttuala, Seppo, Fruttiger, Marcus, Mäkinen, Taija, Eichmann, Anne, Pollard, Jeffrey W., Gerhardt, Holger, Alitalo, Kari
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261765/
https://ncbi.nlm.nih.gov/pubmed/21909098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2331
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