VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR)-2 and VEGFR-3 have been implicated in angiogenic sprouting. Surprisingly, we f...

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Autors principals: Tammela, Tuomas, Zarkada, Georgia, Nurmi, Harri, Jakobsson, Lars, Heinolainen, Krista, Tvorogov, Denis, Zheng, Wei, Franco, Claudio A., Murtomäki, Aino, Aranda, Evelyn, Miura, Naoyuki, Ylä-Herttuala, Seppo, Fruttiger, Marcus, Mäkinen, Taija, Eichmann, Anne, Pollard, Jeffrey W., Gerhardt, Holger, Alitalo, Kari
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261765/
https://ncbi.nlm.nih.gov/pubmed/21909098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2331
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