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Hydrogen exchange mass spectrometry as an analytical tool for the analysis of amyloid fibrillogenesis()

In this study, we have used glucagon as a model system for analyzing amyloid fibrillogenesis by hydrogen exchange MALDI mass spectrometry (HXMS). The hydrogen exchange mass spectrometry data correlated well with the traditional method based on Thioflavin T fluorescence and provided quantitative info...

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Detalhes bibliográficos
Main Authors: Scavenius, Carsten, Ghodke, Shirin, Otzen, Daniel E., Enghild, Jan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261750/
https://ncbi.nlm.nih.gov/pubmed/22267952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.10.001
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