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Post-transcriptional modification of spliceosomal RNAs is normal in SMN-deficient cells
The survival of motor neuron (SMN) protein plays an important role in the biogenesis of spliceosomal snRNPs and is one factor required for the integrity of nuclear Cajal bodies (CBs). CBs are enriched in small CB-specific (sca) RNAs, which guide the formation of pseudouridylated and 2′-O-methylated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261741/ https://ncbi.nlm.nih.gov/pubmed/22124016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030106.111 |
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