Systematic exploration of synergistic drug pairs

Drug synergy allows a therapeutic effect to be achieved with lower doses of component drugs. Drug synergy can result when drugs target the products of genes that act in parallel pathways (‘specific synergy'). Such cases of drug synergy should tend to correspond to synergistic genetic interactio...

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Bibliografiska uppgifter
Huvudupphovsmän: Cokol, Murat, Chua, Hon Nian, Tasan, Murat, Mutlu, Beste, Weinstein, Zohar B, Suzuki, Yo, Nergiz, Mehmet E, Costanzo, Michael, Baryshnikova, Anastasia, Giaever, Guri, Nislow, Corey, Myers, Chad L, Andrews, Brenda J, Boone, Charles, Roth, Frederick P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261710/
https://ncbi.nlm.nih.gov/pubmed/22068327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.71
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