Systematic exploration of synergistic drug pairs

Drug synergy allows a therapeutic effect to be achieved with lower doses of component drugs. Drug synergy can result when drugs target the products of genes that act in parallel pathways (‘specific synergy'). Such cases of drug synergy should tend to correspond to synergistic genetic interactio...

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Bibliographische Detailangaben
Hauptverfasser: Cokol, Murat, Chua, Hon Nian, Tasan, Murat, Mutlu, Beste, Weinstein, Zohar B, Suzuki, Yo, Nergiz, Mehmet E, Costanzo, Michael, Baryshnikova, Anastasia, Giaever, Guri, Nislow, Corey, Myers, Chad L, Andrews, Brenda J, Boone, Charles, Roth, Frederick P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261710/
https://ncbi.nlm.nih.gov/pubmed/22068327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.71
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