Nalaganje...

Molecular Characteristics Predict Clinical Outcomes: Prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene

PURPOSE: To determine if tumor regression following treatment with gefitinib correlates with the presence of sensitizing mutations in EGFR. PATIENTS AND METHODS: Patients with resectable stage I and II non-small cell lung cancer (NSCLC) enriched for the likelihood of EGFR mutation (≤ 15 pack year ci...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rizvi, Naiyer A., Pao, William, Chaft, Jamie E., Ladanyi, Marc, Miller, Vincent A., Krug, Lee M., Azzoli, Christopher G., Bains, Manjit, Downey, Robert, Flores, Raja, Park, Bernard, Rusch, Valerie, Zakowski, Maureen, Heelan, Robert T., Shen, Ronglai, Kris, Mark G.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261615/
https://ncbi.nlm.nih.gov/pubmed/21558399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2102
Oznake: Označite
Brez oznak, prvi označite!