Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair

Wnts are required for cardiogenesis but the role of specific Wnts in cardiac repair remains unknown. In this report, we show that a dynamic Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. Acute ischaemic cardiac injury upregulates Wnt1 that i...

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Main Authors: Duan, Jinzhu, Gherghe, Costin, Liu, Dianxin, Hamlett, Eric, Srikantha, Luxman, Rodgers, Laurel, Regan, Jenna N, Rojas, Mauricio, Willis, Monte, Leask, Andrew, Majesky, Mark, Deb, Arjun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261567/
https://ncbi.nlm.nih.gov/pubmed/22085926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.418
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