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Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair

Wnts are required for cardiogenesis but the role of specific Wnts in cardiac repair remains unknown. In this report, we show that a dynamic Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. Acute ischaemic cardiac injury upregulates Wnt1 that i...

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Detalhes bibliográficos
Main Authors: Duan, Jinzhu, Gherghe, Costin, Liu, Dianxin, Hamlett, Eric, Srikantha, Luxman, Rodgers, Laurel, Regan, Jenna N, Rojas, Mauricio, Willis, Monte, Leask, Andrew, Majesky, Mark, Deb, Arjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261567/
https://ncbi.nlm.nih.gov/pubmed/22085926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.418
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