Wnt1 is a proangiogenic molecule, enhances human endothelial progenitor function, and increases blood flow to ischemic limbs in a HGF-dependent manner

Human endothelial progenitor cells (hEPCs) participate in neovascularization of ischemic tissues. Function and number of hEPCs decline in patients with cardiovascular disease, and therapeutic strategies to enhance hEPC function remain an important field of investigation. The Wnt signaling system, co...

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Главные авторы: Gherghe, Costin M., Duan, Jinzhu, Gong, Jucheng, Rojas, Mauricio, Klauber-Demore, Nancy, Majesky, Mark, Deb, Arjun
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2011
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219217/
https://ncbi.nlm.nih.gov/pubmed/21321190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-172981
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