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Largazole and Its Derivatives Selectively Inhibit Ubiquitin Activating Enzyme (E1)
Protein ubiquitination plays an important role in the regulation of almost every aspect of eukaryotic cellular function; therefore, its destabilization is often observed in most human diseases and cancers. Consequently, developing inhibitors of the ubiquitination system for the treatment of cancer h...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261141/ https://ncbi.nlm.nih.gov/pubmed/22279528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029208 |
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