Zyflamend Sensitizes Tumor Cells to TRAIL-Induced Apoptosis Through Up-Regulation of Death Receptors and Down-Regulation of Survival Proteins: Role of ROS-Dependent CCAAT/Enhancer-Binding Protein-Homologous Protein Pathway

Aim: TNF (tumor necrosis factor)-related apoptosis-inducing ligand (TRAIL), is a selective killer of tumor cells, although its potential is limited by the development of resistance. In this article, we investigated whether the polyherbal preparation Zyflamend(®) can sensitize tumor cells to TRAIL. R...

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Detalhes bibliográficos
Main Authors: Kim, Ji Hye, Park, Byoungduck, Gupta, Subash C., Kannappan, Ramaswamy, Sung, Bokyung, Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261028/
https://ncbi.nlm.nih.gov/pubmed/22004570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.3982
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