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Blockade of Dopamine D4 Receptors Attenuates Reinstatement of Extinguished Nicotine-Seeking Behavior in Rats

Since cloning of the dopamine receptor D4 (DRD4), its role in the brain has remained unclear. It has been reported that polymorphism of the DRD4 gene in humans is associated with reactivity to cues related to tobacco smoking. However, the role of DRD4 in animal models of nicotine addiction has seldo...

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Detalhes bibliográficos
Main Authors: Yan, Yijin, Pushparaj, Abhiram, Le Strat, Yann, Gamaleddin, Islam, Barnes, Chanel, Justinova, Zuzana, Goldberg, Steven R, Le Foll, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260983/
https://ncbi.nlm.nih.gov/pubmed/22030716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.245
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