Blockade of Dopamine D4 Receptors Attenuates Reinstatement of Extinguished Nicotine-Seeking Behavior in Rats

Since cloning of the dopamine receptor D4 (DRD4), its role in the brain has remained unclear. It has been reported that polymorphism of the DRD4 gene in humans is associated with reactivity to cues related to tobacco smoking. However, the role of DRD4 in animal models of nicotine addiction has seldo...

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Bibliographische Detailangaben
Hauptverfasser: Yan, Yijin, Pushparaj, Abhiram, Le Strat, Yann, Gamaleddin, Islam, Barnes, Chanel, Justinova, Zuzana, Goldberg, Steven R, Le Foll, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260983/
https://ncbi.nlm.nih.gov/pubmed/22030716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.245
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