Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4(+) T cells

Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells. DC-asialoglycoprotein receptor (DC-ASGPR), a lectinlike receptor, is a known scavenger receptor. Here, we report that targeting antigens to huma...

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Main Authors: Li, Dapeng, Romain, Gabrielle, Flamar, Anne-Laure, Duluc, Dorothée, Dullaers, Melissa, Li, Xiao-Hua, Zurawski, Sandra, Bosquet, Nathalie, Palucka, Anna Karolina, Le Grand, Roger, O’Garra, Anne, Zurawski, Gerard, Banchereau, Jacques, Oh, SangKon
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260876/
https://ncbi.nlm.nih.gov/pubmed/22213806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110399
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