Glyoxalase I Retards Renal Senescence

Although kidney functions deteriorate with age, little is known about the general morphological alterations and mechanisms of renal senescence. We hypothesized that carbonyl stress causes senescence and investigated the possible role of glyoxalase I (GLO1), which detoxifies precursors of advanced gl...

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Detalhes bibliográficos
Main Authors: Ikeda, Yoichiro, Inagi, Reiko, Miyata, Toshio, Nagai, Ryoji, Arai, Makoto, Miyashita, Mitsuhiro, Itokawa, Masanari, Fujita, Toshiro, Nangaku, Masaomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260855/
https://ncbi.nlm.nih.gov/pubmed/22001178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.023
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