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Sensory neurons derived from diabetic rats have diminished internal Ca(2+) stores linked to impaired re-uptake by the endoplasmic reticulum

Distal symmetrical sensory neuropathy in diabetes involves the dying back of axons, and the pathology equates with axonal dystrophy generated under conditions of aberrant Ca(2+) signalling. Previous work has described abnormalities in Ca(2+) homoeostasis in sensory and dorsal horn neurons acutely is...

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Bibliografiska uppgifter
Huvudupphovsmän: Zherebitskaya, Elena, Schapansky, Jason, Akude, Eli, Smith, Darrell R, Van der Ploeg, Randy, Solovyova, Natasha, Verkhratsky, Alexei, Fernyhough, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Neurochemistry 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260471/
https://ncbi.nlm.nih.gov/pubmed/22168362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110038
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