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Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids

Sulfur amino acids are determinant for the detoxification of paracetamol (N-acetyl-p-aminophenol) through sulfate and glutathione conjugations. Long-term paracetamol treatment is common in the elderly, despite a potential cysteine/glutathione deficiency. Detoxification could occur at the expense of...

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Bibliografiske detaljer
Main Authors: Pujos-Guillot, Estelle, Pickering, Gisèle, Lyan, Bernard, Ducheix, Gilles, Brandolini-Bunlon, Marion, Glomot, Françoise, Dardevet, Dominique, Dubray, Claude, Papet, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260351/
https://ncbi.nlm.nih.gov/pubmed/21340541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9218-4
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