The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial

BACKGROUND: Paracetamol’s (APAP) mechanism of action suggests the implication of supraspinal structures but no neuroimaging study has been performed in humans. METHODS AND RESULTS: This randomized, double-blind, crossover, placebo-controlled trial in 17 healthy volunteers (NCT01562704) aimed to eval...

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Publicado en:Drug Des Devel Ther
Main Authors: Pickering, Gisèle, Kastler, Adrian, Macian, Nicolas, Pereira, Bruno, Valabrègue, Romain, Lehericy, Stéphane, Boyer, Louis, Dubray, Claude, Jean, Betty
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517518/
https://ncbi.nlm.nih.gov/pubmed/26229445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S81004
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