Retinal Expression of Wnt-Pathway Mediated Genes in Low-Density Lipoprotein Receptor-Related Protein 5 (Lrp5) Knockout Mice

Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype in human FEVR patients is recapitulated in Lrp5 k...

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Main Authors: Chen, Jing, Stahl, Andreas, Krah, Nathan M., Seaward, Molly R., Joyal, Jean-Sebastian, Juan, Aimee M., Hatton, Colman J., Aderman, Christopher M., Dennison, Roberta J., Willett, Keirnan L., Sapieha, Przemyslaw, Smith, Lois E. H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260226/
https://ncbi.nlm.nih.gov/pubmed/22272305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030203
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