Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer

BACKGROUND: Preclinical data support further investigation of ascorbic acid in pancreatic cancer. There are currently insufficient safety data in human subjects, particularly when ascorbic acid is combined with chemotherapy. METHODS AND FINDINGS: 14 subjects with metastatic stage IV pancreatic cance...

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Detalhes bibliográficos
Main Authors: Monti, Daniel A., Mitchell, Edith, Bazzan, Anthony J., Littman, Susan, Zabrecky, George, Yeo, Charles J., Pillai, Madhaven V., Newberg, Andrew B., Deshmukh, Sandeep, Levine, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260161/
https://ncbi.nlm.nih.gov/pubmed/22272248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029794
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