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Pharmacodynamic Separation of Gemcitabine and Erlotinib in Locally Advanced or Metastatic Pancreatic Cancer: Therapeutic and Biomarker Results
PURPOSE: Erlotinib marginally improves survival when administered continuously with gemcitabine to patients with advanced pancreatic cancer; however, preclinical data suggest that there is antagonism between chemotherapy and Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors when the...
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| Publicado no: | Int J Clin Oncol |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318776/ https://ncbi.nlm.nih.gov/pubmed/25091263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10147-014-0730-2 |
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