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Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis

BACKGROUND: IL-31 is a pruritogenic cytokine, and IL-33 is an alarmin for damaging inflammation. They together relate to the pathogenesis of atopic dermatitis (AD). Eosinophil infiltration into the inner dermal compartment is a predominant pathological feature of AD. We herein investigated the in vi...

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Bibliografske podrobnosti
Main Authors: Wong, Chun-Kwok, Leung, Karen Ming-Lam, Qiu, Huai-Na, Chow, Joyce Yin-Sau, Choi, Angela On Kei, Lam, Christopher Wai-Kei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260155/
https://ncbi.nlm.nih.gov/pubmed/22272250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029815
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