Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in T47D Breast Cancer Cells and Primary Leiomyoma Cells

BACKGROUND: Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the antiprogestin RU486 inhibits growth of these tissues through an unknown mechanism. Here, we determined the interaction between comm...

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Hauptverfasser: Yin, Ping, Roqueiro, Damian, Huang, Lei, Owen, Jonas K., Xie, Anna, Navarro, Antonia, Monsivais, Diana, Coon V, John S., Kim, J. Julie, Dai, Yang, Bulun, Serdar E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260146/
https://ncbi.nlm.nih.gov/pubmed/22272226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029021
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