Genome-Wide DNA Methylation Indicates Silencing of Tumor Suppressor Genes in Uterine Leiomyoma

BACKGROUND: Uterine leiomyomas, or fibroids, represent the most common benign tumor of the female reproductive tract. Fibroids become symptomatic in 30% of all women and up to 70% of African American women of reproductive age. Epigenetic dysregulation of individual genes has been demonstrated in lei...

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Detaylı Bibliyografya
Asıl Yazarlar: Navarro, Antonia, Yin, Ping, Monsivais, Diana, Lin, Simon M., Du, Pan, Wei, Jian-Jun, Bulun, Serdar E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302826/
https://ncbi.nlm.nih.gov/pubmed/22428009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033284
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