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Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate

BACKGROUND: The surface antigen PfEMP-1 is a key virulence factor of the human malaria parasite implicated in the cytoadherence of Plasmodium falciparum infected erythrocytes to a range of receptors on host endothelium. Among these host receptors, binding to ICAM-1 is related to cerebral malaria. Th...

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Autores principales: Patil, Pradeep R, Gemma, Sandra, Campiani, Giuseppe, Craig, Alister G
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260111/
https://ncbi.nlm.nih.gov/pubmed/22132804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-348
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