Cib2 Binds Integrin α7Bβ1D and Is Reduced in Laminin α2 Chain-deficient Muscular Dystrophy

Mutations in the gene encoding laminin α2 chain cause congenital muscular dystrophy type 1A. In skeletal muscle, laminin α2 chain binds at least two receptor complexes: the dystrophin-glycoprotein complex and integrin α7β1. To gain insight into the molecular mechanisms underlying this disorder, we p...

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Detalhes bibliográficos
Main Authors: Häger, Mattias, Bigotti, Maria Giulia, Meszaros, Renata, Carmignac, Virginie, Holmberg, Johan, Allamand, Valérie, Åkerlund, Mikael, Kalamajski, Sebastian, Brancaccio, Andrea, Mayer, Ulrike, Durbeej, Madeleine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259829/
https://ncbi.nlm.nih.gov/pubmed/18611855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801166200
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