Cholesterol-dependent Separation of the β(2)-Adrenergic Receptor from Its Partners Determines Signaling Efficacy: INSIGHT INTO NANOSCALE ORGANIZATION OF SIGNAL TRANSDUCTION

Determining the role of lipid raft nanodomains in G protein-coupled receptor signaling remains fraught by the lack of assays directly monitoring rafts in native membranes. We thus combined extensive biochemical and pharmacological approaches to a nanoscale strategy based on bioluminescence resonance...

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Detalhes bibliográficos
Main Authors: Pontier, Stéphanie M., Percherancier, Yann, Galandrin, Ségolène, Breit, Andreas, Galés, Céline, Bouvier, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259828/
https://ncbi.nlm.nih.gov/pubmed/18566454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800778200
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