Adenylic Dinucleotides Produced by CD38 Are Negative Endogenous Modulators of Platelet Aggregation

Diadenosine 5′,5‴-P1,P2-diphosphate (Ap2A) is one of the adenylic dinucleotides stored in platelet granules. Along with proaggregant ADP, it is released upon platelet activation and is known to stimulate myocyte proliferation. We have previously demonstrated synthesis of Ap2A and of two isomers ther...

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Библиографические подробности
Главные авторы: Magnone, Mirko, Basile, Giovanna, Bruzzese, Debora, Guida, Lucrezia, Signorello, Maria Grazia, Chothi, Madhu Parakkottil, Bruzzone, Santina, Millo, Enrico, Qi, Ai-Dong, Nicholas, Robert A., Kassack, Matthias U., Leoncini, Giuliana, Zocchi, Elena
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
Mechanisms of Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259817/
https://ncbi.nlm.nih.gov/pubmed/18606819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710568200
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