Adenylic Dinucleotides Produced by CD38 Are Negative Endogenous Modulators of Platelet Aggregation

Diadenosine 5′,5‴-P1,P2-diphosphate (Ap2A) is one of the adenylic dinucleotides stored in platelet granules. Along with proaggregant ADP, it is released upon platelet activation and is known to stimulate myocyte proliferation. We have previously demonstrated synthesis of Ap2A and of two isomers ther...

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Détails bibliographiques
Auteurs principaux: Magnone, Mirko, Basile, Giovanna, Bruzzese, Debora, Guida, Lucrezia, Signorello, Maria Grazia, Chothi, Madhu Parakkottil, Bruzzone, Santina, Millo, Enrico, Qi, Ai-Dong, Nicholas, Robert A., Kassack, Matthias U., Leoncini, Giuliana, Zocchi, Elena
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259817/
https://ncbi.nlm.nih.gov/pubmed/18606819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710568200
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