KIF1Bβ Functions as a Haploinsufficient Tumor Suppressor Gene Mapped to Chromosome 1p36.2 by Inducing Apoptotic Cell Death

Deletion of the distal region of chromosome 1 frequently occurs in a variety of human cancers, including aggressive neuroblastoma. Previously, we have identified a 500-kb homozygously deleted region at chromosome 1p36.2 harboring at least six genes in a neuroblastoma-derived cell line NB1/C201. Amon...

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Autors principals: Munirajan, Arasambattu K., Ando, Kiyohiro, Mukai, Akira, Takahashi, Masato, Suenaga, Yusuke, Ohira, Miki, Koda, Tadayuki, Hirota, Toru, Ozaki, Toshinori, Nakagawara, Akira
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259808/
https://ncbi.nlm.nih.gov/pubmed/18614535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802316200
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