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Structural and Mutational Characterization of the Catalytic A-module of the Mannuronan C-5-epimerase AlgE4 from Azotobacter vinelandii

Alginate is a family of linear copolymers of (1→4)-linked β-d-mannuronic acid and its C-5 epimer α-l-guluronic acid. The polymer is first produced as polymannuronic acid and the guluronic acid residues are then introduced at the polymer level by mannuronan C-5-epimerases. The structure of the cataly...

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Main Authors: Rozeboom, Henriëtte J., Bjerkan, Tonje M., Kalk, Kor H., Ertesvåg, Helga, Holtan, Synnøve, Aachmann, Finn L., Valla, Svein, Dijkstra, Bauke W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259796/
https://ncbi.nlm.nih.gov/pubmed/18574239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804119200
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