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Both WFIKKN1 and WFIKKN2 Have High Affinity for Growth and Differentiation Factors 8 and 11

WFIKKN1 and WFIKKN2 are large extracellular multidomain proteins consisting of a WAP, a follistatin, an immunoglobulin, two Kunitz-type protease inhibitor domains, and an NTR domain. Recent experiments have shown that WFIKKN2 protein binds mature GDF8/myostatin and myostatin propeptide and inhibits...

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Autores principales: Kondás, Katalin, Szláma, György, Trexler, Mária, Patthy, László
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259755/
https://ncbi.nlm.nih.gov/pubmed/18596030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803025200
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