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Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing of the Vibrio cholerae Multifunctional Autoprocessing RTX Toxin

Vibrio cholerae secretes a large virulence-associated multifunctional autoprocessing RTX toxin (MARTX(Vc)). Autoprocessing of this toxin by an embedded cysteine protease domain (CPD) is essential for this toxin to induce actin depolymerization in a broad range of cell types. A homologous CPD is also...

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Autori principali: Prochazkova, Katerina, Satchell, Karla J. Fullner
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259750/
https://ncbi.nlm.nih.gov/pubmed/18591243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803334200
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