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Dependence of Acute Myeloid Leukemia on Adhesion within the Bone Marrow Microenvironment

Acute myeloid leukemia (AML) cells home to the endosteal region of the bone marrow. They interact with bone marrow stromal components including extracellular matrix proteins, glycosaminoglycans, and stromal cells, by which they derive proliferative and growth inhibitory signals. Furthermore, adhesio...

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Detalhes bibliográficos
Autor principal: Becker, Pamela S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259714/
https://ncbi.nlm.nih.gov/pubmed/22346731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/856467
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