Two Heparanase Splicing Variants with Distinct Properties Are Necessary in Early Xenopus Development

Heparanase is an endoglycosidase that cleaves heparan sulfate (HS) side chains from heparan sulfate proteoglycans (HSPGs) present in extracellular matrix and cell membranes. Although HSPGs have many functions during development, little is known of the role of the enzyme that degrades HS, heparanase....

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Autores principales: Bertolesi, Gabriel E., Michaiel, George, McFarlane, Sarah
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259660/
https://ncbi.nlm.nih.gov/pubmed/18397881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708525200
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